Publications

See a complete publications list on PubMed or GoogleScholar

2024

• 110 – Iglesias, M.S., Hou, D.C-F., Reid, J., Schauer, E., Geier, R., Soriaga, A., Sim, L., Gao, L., Whitelegge, J., Kyme, P., Birx, D., Lemire, S., and Cingolani, G. (2024) Cryo-EM analysis of Pseudomonas phage Pa193 structural components. Commun Biol. 2024 Oct 6;7(1):1275. PMCID: PMC11456595
• 109 – Lokareddy RK, Hou CD, Forti F, Iglesias SM, Li F, Pavlenok M, Horner DS, Niederweis M, Briani F, Cingolani G. (2024) Integrative structural analysis of Pseudomonas phage DEV reveals a genome ejection motor. Nat Commun. 5(1):8482. PMCID: PMC10925440
• 108 – Vukovic, I., Barnada, M.S., Ruffin, W.J., Karlin, J., Lokareddy, K.R., Cingolani, G. and McMahon, B.S. (2024) Non-redundant roles for the human mRNA decapping cofactor paralogs DCP1a and DCP1b. Life Sci Alliance. 7(11):e202402938. PMCID: PMC11387620
• 107 – Hayashi, M., Girdhar, A., Ko, Y-H., Kim, M.K, DePierro, A.J., Buchler, R.J., Arunprakash, N., Bajaj, A., Cingolani, G. and Guo, L. (2024) Engineered NLS-chimera downregulates expression of aggregation-prone endogenous FUS. Nat Commun, 15(1):7887. PMCID: PMC11384663
• 106 – Ko, Y-H., Lokareddy, K.R., Doll, G.C., Yeggoni, P.D., Girdhar, A. Mawn, I., Klim, R.J., Rizvi, F.N., Meyers, R., Gillilan, E.R., Guo, L. and Cingolani, G. (2024) Single acetylation-mimetic mutation in TDP-43 Nuclear Localization Signal disrupts importin α1/β signaling. J Mol Biol, 436(20):168751. PMCID: PMC11443512
• 105 – Iglesias, M.S., Li, F., Briani, F. and Cingolani, G. (2024) Viral genome delivery across bacterial cell surfaces. Annu Rev Microbiol. Volume 78. doi: 10.1146/annurev-micro-041222-124727
• 104 – Yang, R., Ko, Y-H., Li, F., Lokareddy, K.R., Hou D.C-F., Kim, C., Klein, S., Antolínez, S., Marín, F.J., Pérez-Segura, C., Jarrold, M.F., Zlotnick, A., Hadden-Perilla, A.J. and Cingolani, G. (2024) Structural basis for nuclear import of Hepatitis B Virus (HBV) nucleocapsid core. Science Advances. 10(2):eadi7606. PMCID: PMC10780889
• 103 – David, Hou D.C-F., Li, F., Iglesias, S., and Cingolani, G. (2024) Use of localized reconstruction to visualize the Shigella-virus Sf6 tail apparatus. Methods in Mol Bio, 2738:215-228. PMCID: PMC10655839 

2023

• 102 – Iglesias, M.S., Lokareddy, K.R., Yang, R., Li, F., Yeggoni, P.D., Hou D.C-F., Leroux, N.M., Cortines, R.J., Leavitt, C.J, Bird, M., Casjens, R.S., White, S., Teschke, M.C., and Cingolani, G. (2023) Molecular Architecture of Salmonella Typhimurium Virus P22 Genome Ejection Machinery. J. Mol Biol. 435(24):168365. PMCID: PMC10842050.
• 101 – Li, F., Hou D.C-F., Lokareddy, K.R., Yang, R., Forti, F., Briani, F., and Cingolani, G. (2023) High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217, Nat Commun, 14(1):4052; PMCID: PMC10329688

2022

• 100 – Li, F., David, Hou C-F, Yang, R., Whitehead R., Teschke, M.C., and Cingolani, G. (2022) High-resolution cryo-EM structure of the Shigella-virus Sf6 genome-delivery tail machine at 2.7 Å resolution, Science Advances, 8(49):eadc9641. PMCID: PMC9728967
• 99 – Doll, G.S. and Cingolani, G. (2022) Importin α/β and the tug of war to keep TDP-43 in solution: quo vadis?BioEssays, 00, e2200181. https://doi.org/bies.202200181. PMCID: PMC9969346
• 98 – Lokareddy, R.K., David, Hou C-F, Li, F., Yang, R. and Cingolani, G. (2022) Viral Small Terminase: a divergent structural framework for a conserved biological function. Viruses. 14(10), 2215; https://doi.org/10.3390/v14102215. PMCID: PMC9611059
• 97 – Lokareddy, R.K., Hou C-F.D., Doll, G.S., Li, F., Gillilan, R.E., Forti, F., Horner, S.D., Briani, F. and Cingolani, G. (2022) Terminase subunits from the Pseudomonas-phage E217. J. Mol Biol. 434(20):167799. PMCID: PMC10026623
• 96 – Doll, G.S., Meshkin, M., Bryer, J.A., Li, F., Ko, Y-H., Lokareddy, R.K., Gillilan, R.E., Gupta, K., Perilla, R.J., and Cingolani, G. (2022) Recognition of the TDP-43 Nuclear Localization Signal by importin α1/b. Cell Reports. 39(13):111007. PMCID: PMC9290431
• 95 – Zhang, L., Kent, E.J., Whitaker, M., Young C.D., Herrmann, D., Aleshin, E.A., Ko, Y-H., Cingolani, G., Saad, S.J., Moody, D.B., Marassi, M.F., Ehrt, S., and Niederweis, M. (2022) A periplasmic cinched protein is required for siderophore secretion and virulence of Mycobacterium tuberculosis. Nat Commun. 13(1):2255. PMCID: PMC9042941
• 94 – Florio, T.J., Lokareddy, R.K., Yeggoni, P.D., Sankhala, R.S., Ott, C., Gillilan, R.E., and Cingolani, G. (2022) Differential recognition of canonical NF-κB dimers by Importin α3. Nat Commun. 13(1):1207. PMCID: PMC8904830
• 93 – Hou C-F.D., Swanson, N.A., Li, F., Yang, R., Lokareddy, R.K., and Cingolani, G. (2022) Cryo-EM structure of a kinetically trapped dodecameric portal protein from the Pseudomonas-phage PaP3. J. Mol Biol. 434(9):167537. PMCID: PMC9066412
• 92 – Swanson, N.A., Hou C-F.D., and Cingolani, G. (2022) Viral ejection proteins: mosaically conserved, conformational gymnasts. Microorganisms. 10(3):504. PMCID: PMC8954989

2021

• 91 – Swanson, N.A., Lokareddy, R.K., Li, F., David, Hou C-F, Pavlenok, M., Niederweis, M., and Cingolani, G. (2021) Expression and purification of phage T7 ejection proteins for cryo-EM analysis. STAR Protocols. 2(4):100960. PMCID: PMC8605104
• 90 – Friedrich, L., Cingolani, G., Ko, YH., Iaselli, M., Miciaccia, M., Perrone, M.G., Neukirch, K., Bobinger, V., Merk, D., Hofstetter, R.K., Werz, O., Koeberle, A., Scilimati, A., and Schneider, G. (2021) Learning from Nature: From a Marine Natural Product to Synthetic Cyclooxygenase-1 Inhibitors by Automated De Novo Design. Advanced Science (Weinh). e2100832. PMCID: PMC8373093 
• 89 – Swanson, N.A., Lokareddy, R.K., Li, F., David, Hou C-F, Leptihn, S., Pavlenok, M., Niederweis, M., Pumroy, R.A., Moiseenkova-Bell, V.Y., Cingolani, G. Cryo-EM Structure of the Periplasmic Tunnel of T7 DNA-Ejectosome at 2.7 Å resolution. Molecular Cell. 81(15):3145-3159. PMCID: PMC8349896
• 88 – Miciaccia, M., Belviso, B.D., Iaselli, M., Cingolani, G., Ferorelli, S., Cappellari, M., Loguercio, P.P., Perrone, MG., Caliandro, R., and Scilimati, A. (2021) Three-dimensional structure of human cyclooxygenase (hCOX)-1. Sci Rep 11(1):4312. PMCID: PMC7900114

2020

• 87 – Niazi, M., Florio, T.J., Yang, R., Lokareddy, R.K., Swanson, N.A. Gillilan, R.E. and Cingolani, G. (2020) Biophysical analysis of Pseudomonas-phage PaP3 small terminase suggests a mechanism for sequence-specific DNA-binding by lateral interdigitation. Nucleic Acid Res. 48(20):11721-11736. PMCID: PMC7672466.
• 86 – Lokareddy, R.K., YH., R., Hong, N., Doll, S.G., Paduch, M., Niederweis, M., Kossiakoff, A.A. and Cingolani, G. (2020) Recognition of an α-helical hairpin in P22 large terminase by a synthetic antibody fragment. Acta Cryst. D. 76(Pt 9):876-888. PCMID: PMC7466751.
• 85 – Fisher, C.R., Lowe, D.E., Smith, T.G., Yang, Y., Hutson, C.L., Wirblich, C., Cingolani, G., and Schnell, M.J. (2020) Lyssavirus Vaccine with a Chimeric Glycoprotein Protects across Phylogroups. Cell Rep. 32(3):107920. PMCID: PMC7371069.
• 84 – De Dominici, M., Porazzi, P., Xiao, Y., Chao, A., Tang, H.Y., Kumar, G., Fortina, P., Spinelli, O., Rambaldi, A., Peterson, L.F., Petruk, S., Barletta, C., Mazo, A., Cingolani, G., Salvino, J.M., Calabretta, B. (2020) Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and independent effects by CDK6-specific PROTACs. Blood. 135(18):1560-1573. PMCID: PMC7193186.

2019

• 83 – Mitra, A., Ko, YH., Cingolani, G., and Niederweis, M. (2019) Heme and hemoglobin utilization by Mycobacterium tuberculosis.  Nat Commun. 10(1):4260. PMCID:PMC6751184
• 82 – Dedeo, C.L., Cingolani G., Teschke, C.M. (2019) Portal Protein: The Orchestrator of Capsid Assembly for the dsDNA Tailed Bacteriophages and Herpesviruses. Annu Rev Virol. (6)1:141-160. PMCID: PMC6947915
• 81 – Cingolani, G., McCauley, M., Lobley, A., Bryer, A.J., Wesolowski, J., Greco, D.L., Lokareddy, R.K., Ronzone, E., Perilla, J.R. and Paumet, F. (2019) Structural basis for the homotypic fusion of chlamydial inclusions by the SNARE-like protein IncA. Nat Commun. 10(1):2747. PMCID: PMC6588587
• 80 – Sharp, A.K., Lu, XJ., Cingolani, G. and Harvey S.C. (2019) DNA Conformational Changes Play a Force-Generating Role during Bacteriophage Genome Packaging.  Biophys J. 116(11):2172-2180. PMCID: PMC6554637
• 79 – Florio T., Lokareddy R.K., Gillilan R. and Cingolani, G. (2019) Molecular architecture of the inositol phosphatase Siw14. Biochemistry. 58(6):534-545. PMCID: PMC6526948

2018

• 78 – Swanson, A.N. and Cingolani, G. (2018) A tail of phage adhesins. Structure. 26(12):1565-1567.
• 77 – Phillips T., Tio C.W., Omerza G., Rimal A., Lokareddy R.K., Cingolani, G. and Winter E. (2018) RNA recognition-like motifs activate a MAPK. Biochemistry. 57(50):6878-6887. PMCID: PMC6457901
• 76 – Rodriguez-Bravo, V., Pippa, R., Song, W.M., Carceles-Cordon, M., Dominguez-Andres, A., Fujiwara, N., Woo, J., Koh, A.P., Ertel, A., Lokareddy, R.K., Cuesta-Dominguez, A., Kim, R.S., Rodriguez-Fernandez, I., Li, P., Gordon, R., Hirschfield, H., Prats, J.M., Reddy, E.P., Fatatis, A., Petrylak, D.P., Gomella, L., Kelly, W.K., Lowe, S.W., Knudsen, K.E., Galsky, M.D.,  Cingolani, G., Lujambio, A., Hoshida, Y., and Domingo-Domenech, J. (2018) Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import. Cell. 174(5):1200-1215. PMCID: PMC6150493
• 75 – Parent, K.N., Schrad J.R. and Cingolani, G. (2018) Breaking symmetry in viral icosahedral capsids as seen through the lenses of X-ray crystallography and cryo-electron microscopy. Viruses 10(2). pii: E67. PMCID: PMC5850374

2017

• 74 – Sankhala, R.S., Lokareddy, R.K., Begum S., Pumroy, A.R., Gillilan, E.R. and Cingolani, G. (2017) Three-dimensional context rather than NLS amino acid sequence determines importin α subtype specificity for RCC1. Nat Commun. 8(1):979. PMCID: PMC5645467
• 73 – Wu, W., Sankhala, S.R., Florio, J.T., Zhou, L., Nguyen, L.T.N., Lokareddy, R.K., Cingolani, G. and Pante, N. (2017) Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin α isoforms. Scientific Reports. 17(1):11381. PMCID: PMC5595889
• 72 – Cingolani, G., Panella, A., Perrone, MG., Vitale, P., Di Mauro, G., Fortuna, C., Armen, R., Ferorelli, S., Smith, W. and Scilimati, A. (2017) Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6). Eur J Med Chem. 138:661-668. PMCID: PMC5992922
• 71 – Motwani, T., Lokareddy, R.K., Dunbar, A.C., Cortines, R.J., Jarrold, F. M., Cingolani, G. and Teschke, C.M. (2017) A viral scaffolding protein triggers portal ring oligomerization and incorporation during procapsid assembly. Science Advances. 3: e1700423. PMCID: PMC5529062
• 70 – Lokareddy, R.K., Sankhala, R.S., Roy, A., Afonine, P.V., Motwani, T., Teschke, C.M., Parent, K.N. and Cingolani, G. (2017) Portal protein functions akin to a DNA-sensor that couples genome-packaging to icosahedral capsid maturation. Nat Commun. 8:14310. PMCID: PMC5290284
• 69 – Rogers, C., Fernandes-Alnemri, T., Mayes, L., Alnemri, D., Cingolani, G. and Alnemri, E.S. (2017) Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death. Nat Commun. 8:14128. PMCID: PMC5216131

2016

• 68 – Sankhala, R.S., Lokareddy, R.K. and Cingolani, G. (2016) Divergent Evolution of Nuclear Localization Signal Sequences in Herpesvirus Terminase Subunits. J Biol Chem. 291(21):11420-33. PMCID: PMC4900285
• 67 – Riccio, A.A., Cingolani, G. and Pascal, J.M. (2016) PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damage. Nucleic Acids Res. 44(4):1691-702. PMCID: PMC4770219
• 66 – Bhardwaj, A., Sankhala, R.S., Olia, A.S., Brooke, D., Casjens, S.R., Taylor, J.D., Prevelige, P.E. Jr. and Cingolani, G. (2016) Structural plasticity of the protein plug that traps newly packaged genomes in podoviridae virions. J Biol Chem. 291(1):215-26. PMCID: PMC4697157

2015

• 65 – Sankhala, R.S., Lokareddy, R.K. and Cingolani, G. (2015) A Greasy Aid to Capsid Assembly: Lessons from a Salty Virus. Structure. 23(10):1777-1779. PMID: 26445488
• 64 – McNulty, R., Lokareddy, R.K., Roy, A., Yang, Y., Lander, G., Heck, A.J., Johnson, J.E. and Cingolani, G. (2015) Architecture of the Complex formed by Large and Small Terminase Subunits from Bacteriophage P22. J. Mol. Biol. 427(20):3285-99. PMCID: PMC4587339
• 63 – Sun, J., Siroy, A., Lokareddy, K.R., Speer, A., Doornbos, K.S., Cingolani, G. and Niederweis, M. (2015) The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD+. Nature Struc Mol Biol. 22(9):672-8. PMCID: PMC4560639
• 62 – Kralt, A., Jagalur, N.B., van den Boom, V., Lokareddy, R.K., Steen, A., Cingolani, G., Fornerod, M., Veenhoff, L.M. (2015) Conservation of inner nuclear membrane targeting sequences in mammalian Pom121 and yeast Heh2 membrane proteins. Mol Biol Cell. 26(18):3301-12. PMCID: PMC4569319
• 61 – Hwang, B., McCool, K., Wan, J., Wuerzberger-Davis, S.M., Young, E.W., Choi, E.Y., Cingolani, G., Weaver, B.A., Miyamoto, S.(2015) IPO3 mediated nonclassical nuclear import of NEMO drives DNA damage-dependent NF-κB activation. J Biol Chem. 290(29):17967-84. PMCID: PMC4505044
• 60 – Liao, Z., Gu, L., Vergalli, J., Mariani, S.A., De Dominici, M., Lokareddy, R.K., Dagvadorj, A., Purushottamachar, P., McCue, P.A., Trabulsi, E., Lallas, C.D., Gupta, S., Ellsworth, E., Blackmon, S., Ertel, A., Fortina, P., Leiby, B., Xia, G., Rui, H., Hoang, D.T., Gomella, L.G., Cingolani, G., Njar, V., Pattabiraman, N., Calabretta, B., Nevalainen, M.T. (2015) Structure-based screen identifies a potent small-molecule inhibitor of Stat5a/b with therapeutic potential for prostate cancer and chronic myeloid leukemia. Mol Cancer Ther. 14:1777-1793. PMCID: PMC4547362
• 59 – Lokareddy, K.R., Hapsari R.A., van Rheenen, M., Pumroy, R.A., Bhardwaj, A., Steen, A., Veenhoff, L.M., and Cingolani, G. (2015) Distinctive properties of the Nuclear Localization Signals of Inner Nuclear Membrane proteins Heh1 and Heh2. Structure. 23(7):1305-16. PMCID: PMC4768490
• 58 – Sankhala, S.R., Koksal, C.A., Ho, L., Nitschke, F., Minassian, A.B. and Cingolani, G. (2015) Dimeric quaternary structure of human laforin. J Biol Chem. 290(8):4552-559. PMCID: PMC4335197
• 57 – Pumroy, R.A. and Cingolani, G. (2015) Diversification of importin alpha isoforms in cellular trafficking and disease state. Biochemical J. 466(1):13-28. PMCID: PMC4405237
• 56 – Pumroy, R.A., Ke, S., Hart, D.J., Zachariae, U. and Cingolani, G. (2015) Molecular determinants for nuclear import of Influenza A PB2 by importin α isoforms 3 and 7. Structure. 23(2): 374-384. PMCID: PMC4346194

2014

• 55 – Aggeli, D., Kish-Trier, E., Lin, M.C., Haarer, B., Cingolani, G., Cooper, J.A., Wilkens, S. and Amberg, D.C. (2014) Coordination of the Filament Stabilizing Versus Destabilizing Activities of Cofilin Through its Secondary Binding Site on Actin. Cytoskeleton. 71(6):361-79. PMCID: PMC4241054
• 54 – Lieu, K.G., Shim, E.H., Wang, J., Lokareddy, R.K., Tao, T., Cingolani, G. Zambetti, G.P., and Jans, D.A. (2014) The p53-induced Factor Ei24 Inhibits Nuclear Import through an Importin beta-binding-like Domain. J. Cell Biol. 205(3):301-12. PMCID: PMC4018778
• 53 – Sankhala, S.R., Lokareddy, K.R. and Cingolani, G. (2014) Structure of Human PIR1, an Atypical Dual Specificity Phosphatase. Biochemistry. 53(5):862-71. PMCID: PMC3985963
• 52 – Bhardwaj, A., Casjens, S.R. and Cingolani, G. (2014) Exploring the atomic structure and conformational flexibility of a 320A long engineered viral fiber using X-ray crystallography. Acta Cryst. D70: 342-353. PMCID: PMC3940195
• 51 – Bhardwaj, A., Olia, A.S. and Cingolani, G. (2014) Architecture of Viral Genome-Delivery Molecular Machines. Curr Opin Struct Biol. 25:1-8. PMCID: PMC4040186

2013

• 50 – Pumroy, R. and Cingolani, G. (2013) Jamming up the “beta-staple”: Regulation of SIRT1 activity by its C-terminal regulatory segment (CTR). J. Mol. Biol. pii: S0022-2836(13)00724-9. PMCID: PMC4405232
• 49 – Smith F.J., Pau, V.P., Cingolani, G., and Rothberg, B.S. (2013) Structural basis of allosteric interactions among Ca2+-binding sites in a K+ channel RCK domain. Nat Commun. 4:2621. PMID: 24126388
• 48 – Leavitt, J.C. Gogokhia, L., Gilcrease, E.B., Bhardwaj, A., Cingolani, G. and Casjens, S.R. (2013) The tip of the tail needle affects the rate of DNA delivery by bacteriophage P22. PLOS One. 8(8):e70936. PMCID: PMC3741392
• 47 – Lokareddy, K.R., Bhardwaj, A. and Cingolani, G. (2013) Atomic structure of dual-specificity phosphatase 26, a novel p53 phosphatase. Biochemistry. 52(5):938-48. PMCID: PMC3619938

2012

• 46 – Smith, F.J., Pau, V.P., Cingolani, G. and Rothberg, B.S. (2012) Crystal Structure of a Ba2+-bound gating ring reveals elementary steps in RCK domain activation. Structure. 20(12):2038-47. PMCID: PMC3518701
• 45 – Roy, A., Hutcheon, L., Duncan, T.M. and Cingolani, G. (2012) Improved crystallization of Escherichia coli ATP synthase catalytic complex (F1) by introducing a phosphomimetic mutation in subunit ε. Acta Cryst. F. 68, 1229-1233. PMCID: PMC3490465
• 44 – Roy, A. and Cingolani, G. (2012) Structure of P22 headful packaging nuclease. J Biol Chem. 287(33):28196-205. PMCID: PMC3431676
• 43 – Roy, A., Bhardwaj, A., Datta, P., Lander, G.C. and Cingolani, G. (2012) Small terminase couples viral DNA-binding to genome-packaging ATPase activity. Structure. 20(8):1403-13. PMCID: PMC3563279
• 42 – Pumroy, R.A., Nardozzi, J., Hart, D.J., Root, M.J. and Cingolani, G. (2012) Nup50 stabilizes the closed conformation of arm 10 in importin a5. J Biol Chem. 287(3):2022-31. PMCID: PMC3265882

2011

• 41 – Lott, K., Bhardwaj, A., Sims, P. and Cingolani, G. (2011) A minimal Nuclear Localization Signal in human phospholipid Scramblase 4 that binds only the minor binding site in importin a. J Biol Chem. 286(32):28160-9. PMCID: PMC3151061
• 40 – Bhardwaj, A., Molineux, J.I., Casjens, S.R. and Cingolani, G. (2011) Atomic Structure of Sf6 Tail Needle Knob. J Biol Chem. 286(35):30867-77. PMCID: PMC3162447
• 39 – Cingolani, G. and Duncan, T.M. (2011) Structure of the ATP synthase catalytic complex (F1) from Escherichia coli in an auto-inhibited conformation. Nature Struc Mol Biol. 18(6):701-7. PMCID: PMC3109198. Faculty of 1000 “exceptional read”.
• 38 – Olia, A.S, Prevelige Jr., P.E., Johnson, J.E. and Cingolani, G. (2011) Three-dimensional structure of a viral genome-delivery portal vertex. Nature Struc Mol Biol. 18(5):597-603. PMCID: PMC3087855
• 37 – Tang, J., Lander, G., Olia, A.S, Prevelige Jr., P.E., Cingolani, G., Casjens, S., Baker, T.S. and Johnson, J.E. (2011) Peering down the barrel of a bacteriophage portal – the genome packaging and release valve in P22. Structure. 19(4):496-502. PMCID: PMC3075339
• 36 – Koksal, C.A., and Cingolani, G. (2011) Dimerization of Vaccinia virus VH1 is essential for dephosphorylation of STAT1 at tyrosine 701. J Biol Chem. 286(16):14373-82. PMCID: PMC3077637
• 35 – Roy, A., Bhardwaj, A., and Cingolani, G. (2011) Crystallization of the Nonameric Small Terminase Subunit of Bacteriophage P22. Acta Cryst. F. 67, 104-110. PMCID: PMC3079985
• 34 – Lott, K. and Cingolani, G. (2011) The IBB-domain as a master regulator of nucleocytoplasmic transport. Biochim Biophys Acta. 1813(9):1578-92. PMCID: PMC3037977

2010

• 33 – Nardozzi, J., Lott, K. and Cingolani, G. (2010) Phosphorylation meets Nuclear Import: a review. Cell Communication and Signaling. 8(1):32. PMCID: PMC3022542
• 32 – Nardozzi, J., Wenta, N., Yasuhara, N., Vinkemeier, U. and Cingolani, G. (2010) Molecular basis for the recognition of phosphorylated STAT1 by importin a5. J. Mol. Biol. 402(1):83-100. PMCID: PMC2930068
• 31 – Bhardwaj, A. and Cingolani, G. (2010) Conformational selection in the recognition of snurportin IBB-domain by importin b. Biochemistry 49(24):5042-7. PMCID: PMC6013741
• 30 – Lott, K., Bhardwaj, A., Mitrousis, G., Pante, N., and Cingolani, G. (2010) The importin beta binding domain modulates avidity of importin b for the nuclear pore complex. J. Biol. Chem. 285(18):13769-80. PMCID: PMC2859540

2009

• 29 – Bhardwaj, A., Walker-Kopp, N., Casjens, S.R., and Cingolani, G. (2009) An evolutionarily conserved family of virion tail needles related to bacteriophage P22 gp26: correlation between structural stability and length of the a-helical trimeric coiled-coil. J. Mol. Biol. 391(1):227-45. PMCID: PMC2713385
• 28 – Mitrea, D.M., Butler, J.S., Mitrousis, G., Cingolani, G. and Loh, S. N. (2009). Structural and Thermodynamic Analysis of Conformationally-Strained Circular Permutants of Barnase. Biochemistry. PMCID: PMC275661448(15):3497-507.
• 27 – Koksal, A., Nardozzi, J., and Cingolani, G. (2009) Dimeric quaternary structure of the prototypical dual specificity phosphatase VH1. J. Biol. Chem. 284(15):10129-37. PMCID: PMC2665067
• 26 – Olia, S.A., Casjens, S., and Cingolani, G. (2009) Structural Plasticity of the phage P22 tail-needle gp26 probed with Xenon Gas. Protein Science. 18(3):537-548. PMCID: PMC2760360

2008

• 25 – Olia, S.A., and Cingolani, G. (2008) A shifty stop for a hairy tail. Mol. Microbiology, 70(3):549-53. PMCID: PMC2779026
• 24 – Bhardwaj, A., Walker-Kopp N, Wilkens, S., and Cingolani, G. (2008) Foldon-guided self-assembly of ultra stable protein fibers. Protein Science 17(9):1475-85. PMCID: PMC2525528
• 23 – Lorenzen, K., Olia, S.A., Uetrecht, C.,  Cingolani, G., and Heck, A.J.R. (2008). Determination of stoichiometry and conformational changes in the first step of the P22 tail assembly. J. Mol. Biol. 379(2):385-96. PMCID: PMC2768609
• 22 – Mitrousis, G., Olia, S.A., Walker and Cingolani, G. (2008). Molecular basis for the recognition of snurportin 1 by importin b. J. Biol. Chem. 283(12):7877-84. PMID: 18187419
• 21 – Zheng, H., Olia, S.A., Hankins, M., Andrews, S., Cingolani, G., and Gonen, T, (2008). A conformational switch in bacteriophage P22 portal protein primes genome injection. Molecular Cell. 29(3), 376-383. PMCID: PMC3936403

2007

• 20 – Olia, S.A., Casjens, S. and Cingolani, G. (2007) Structure of Phage P22 Cell Envelope Penetrating Needle. Nature Struc Mol Biol. 14(12), 1221-1226.
• 19 – Olia, S.A., Bhardwaj, A., Joss, L., Casjens, S., and Cingolani, G. (2007) The role of gene 10 protein in the hierarchical assembly of the bacteriophage P22 portal vertex structure. Biochemistry. 46(30), 8776-8784.
• 18 – Bhardwaj, A., Olia, S.A., Walker-Kopp N, and Cingolani, G. (2007) Domain organization and polarity of tail needle gp26 in the portal vertex structure of bacteriophage P22. J. Mol. Biol. 371(2), 374-87.

2006

• 17 – Olia, A., Al-Bassam, J., Winn-Stapley, D.A., Joss, L., Casjens, S., and Cingolani, G. (2006) Binding induced stabilization and oligomerization of portal closure factor gp4 in the assembly pathway of phage P22 tail. J. Mol. Biol. 363, 558–576.
• 16 – Cingolani, G., Andrews, D., and Casjens, S. (2006) Crystallogenesis of bacteriophage P22 tail accessory factor gp26 at acidic and neutral pH. Acta Cryst. F 62, 477–482.
• 15 – Taylor, D.J., Speir, J.A., Reddy, V., Cingolani, G., Pringle, F.M., Ball, L.A., and Johnson, J.E. (2006) Preliminary X-ray characterization of authentic providence virus and attempts to express its coat protein gene in recombinant baculovirus. Arch Virol. 151(1):155-65.

2005

• 14 – Andrews D, Butler JS, Al-Bassam J, Joss L, Winn-Stapley DA, Casjens S, and Cingolani, G. (2005) Bacteriophage P22 Tail Accessory Factor GP26 Is a Long Triple-stranded Coiled-coil. J. Biol. Chem. 280(7): 5929-33.
• 13 – Chen MH, Ben-Efraim I, Mitrousis G, Walker-Kopp N, Sims PJ, and Cingolani, G. (2005) Phospholipid scramblase 1 (PLSCR1) contains a non-classical nuclear localization signal with unique binding site in importin a. J. Biol. Chem. 280(11):10599-606.
• 12 – Tang L., Marion W., Cingolani, G., Prevelige P.E. Jr., and Johnson J.E. (2005) Three-dimensional structure of the bacteriophage P22 tail machine EMBO J. 24(12):2087-95.

2001 – 2004

• 11 – Wodrich, H., Guan, T., Cingolani, G., von Seggern, D., Nemerow, G., and Gerace, L. (2003). Switch from capsid protein import to adenovirus assembly by cleavage of nuclear transport signals. EMBO J. 22 (23): 6150-6162.
• 10 – Bednenko, J., Cingolani, G., and Gerace, L. (2003). Importin beta contains a COOH-terminal nucleoporin binding region important for nuclear import. J. Cell Biol. 162(3): 391-401. Faculty of 1000 “recommended read”.
• 9 – Koerner, C., Guan, T., Gerace, L. and Cingolani, G. (2003). Synergistic effects of silent and hot spot mutations in importin b reveals a dynamic mechanism for recognition of a nuclear localization signal. J. Biol. Chem. 278 (18): 16216-16221.
• 8 – Cingolani, G., and Gerace, L. (2003). Molecular basis of nucleocytoplasmic transport. Handbook of Cell Signaling, Academic Press, Vol. 3(330): 419-429.
• 7 – Bednenko, J., Cingolani, G., and Gerace, L. (2003). Nucleocytoplasmic transport: navigating the channel (NPC). Traffic, 4(3): 27-135.
• 6 – Cingolani, G., Bednenko, J., Gillespie, M., and Gerace, L. (2002). Molecular basis for the recognition of a non-classical nuclear localization signal (NLS) by importin b. Molecular Cell, 10: 1345-1353.
• 5 – Cingolani, G., Moore, S., Privilege, P.E., and Johnson, J. (2002). Preliminary crystallographic analysis of the bacteriophage P22 portal protein. J. Struc. Biology, 139: 46-54.

1997 – 2000

• 4 – Cingolani, G., Lashuel, H., Gerace, L., and Mueller, C.W. (2000). Nuclear import factors importin a and importin b undergo mutually induced conformational changes upon association. FEBS Lett., 484(3): 291-298.
• 3 – Chook, Y.M, Cingolani, G., Conti, E., Stewart, M., Vetter, I., and Wittinghofer, A. (1999). Pictures in cell biology. Structures of nuclear-transport components. Trends Cell Biol., 9(8): 310-311
• 2 – Cingolani, G., Petosa, C., Weis, K., and Mueller, C.W. (1999). Structure of importin b bound to the IBB domain of importin a. Nature, 399(6733): 221-229.
• 1 – Cingolani, G., Capaccio, L., D’Elia, D., and Gadaleta, G. (1997). In organello footprinting analysis of rat mitochondrial DNA: protein interaction upstream of the Ori-L. Biochem Biophys Res Commun, 231(3): 856-860.