Structure Gallery

Gallery of Structures Solved in the Lab

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 Immature ProCapsid conformation of P22 Portal Protein

 Procapsid-portal

       PDB entries: 5JJ3, 5JJ1

       Lokareddy et al.,          Nature Comm, 2017

HK620 and P22 tail  needles crystallized at different pHs

Tail-Needles

 PDB entries: 4ZKP, 4ZKU, 4ZXQ, 5BU5, 5BVZ, 5BU8

Bhardwaj et al., J. Biol. Chemistry, 2016

 Pom121 membrane protein NLS bound to importin α

 Pom121-NLS

 PDB entry: 4YI0

                   Kralt et al.,                Mol. Biol. Cell, 2015

Heh1 and Heh2 membrane protein NLS bound to yeast importin α
Kap60-Heh2NLS

 PDB entry: 4PVZ, 4XZR

Lokareddy et al.,
Structure, 2015

Mycobacterium Tuberculosis TNT-IFT Complex

TNT-IFT-1

PDB entry: 4QLP

Sun et al.,
Nat. Struct. Mol. Biol., 2015

Importin α isoforms 1, 3, 7 bound to Influenza PB2

 Importin-alpha isoforms 1, 3 and 7 bound to Influenza PB2

PDB entry: 4UAD, 4UAE, 4UAF

Pumroy et al.,
Structure, 2015

Phosphatase domain of Human Laforin

 Laforin-DSP

PDB entry: 4R30

Sankhala et al.,
J. Biol. Chemistry, 2015
Human RNA Phosphatase PIR1
PIR1-structure

PDB entry: 4MBB, 4NYH

Sankhala et al.,
Biochemistry, 2014
 Human p53-phosphatase
DUSP26
 DUSp26.png

PDB entry: 4HRF

Lokareddy et al.,
Biochemistry, 2013
P22 Headful Packaging Nuclease
P22HeadfulPackaging

 PDB entry: 4DKW

Roy et al.,
J. Biol. Chemistry, 2012
Human Importin α5 bound to Nup50
HumanImportin5

PDB entry: 3TJ3

Ruth et al.,
J. Biol. Chemistry, 2012
P22 nonameric
Small terminase subunit 

 

nonameric

PDB entry: 3P9A

Roy et al.,
Structure, 2012
Mammalian Importin α1 bound to PLSCR4 minimal NLS
MamalainImportin1

PDB entry: 3Q5U

Lott et al.,
J. Biol. Chemistry, 2011

E.coli  F1 ATPase inhibited by subunit ε

F1-structure

PDB entry: 3OAA

Cingolani and Duncan,
Nat. Struct. Mol. Biol., 2011

Structure of phage Sf6 Tail Needle Knob

Sf6-Tail-Needle-Knob

PDB entry: 3RWN, 4K6B

Bhardwaj et al.,
J. Biol. Chemistry, 2011
Full length dodecameric P22 Portal Protein
full-length-dodecamericP22

PDB entry: 3LJ5

Olia et al.,
Nat. Struct. Mol. Biol., 2011
Dodecameric P22 Portal Protein Core bound to twelve GP4s
dodecamericP22

PDB entry: 1VT0, 3LJ4

Olia et al.,
Nat. Struct. Mol. Biol., 2011
 Open and closed conformation of Importin β bound to sIBB-domain
3LWW

PDB entry: 3LWW

Bhardwaj et al.,
Biochemistry, 2010
A circular permutant of
Barnase
3DA7

PDB entry: 3DA7

Butler et al.,
Biochemistry, 2009
Vaccinia Virus Dual Specificity Phosphatase VH1
3CM3-2RF6

PDB entry: 3CM3, 2RF6

Koksal et al.,
J. Biol. Chemistry, 2009
Phage P22 Tail Needle Gp26
2POH-3C9I

PDB entry: 2POH, 3C9I

Olia et al.,
Nat. Struct. Mol. Biol., 2007
Human Importin β bound to snurportin IBB-domain
2P8Q-2Q5D

PDB entry: 2P8Q, 2Q5D

Mitrousis et al.,
J. Biol. Chemistry, 2008
Mammalian Importin α bound to Scramblase 1 NLS
1Y2A

PDB entry: 1Y2A

Chen et al.,
J. Biol. Chemistry, 2005
Human Importin β HEATs (1-11) bound to the PTHrP-NLS
1M5N

PDB entry: 1M5N

Cingolani et al.,
Molecular Cell, 2002
Human Importin β bound to importin αIBB-domain
Importinb aIBB

PDB entry: 1QGK, 1QGR

Cingolani et al.,
Nature, 1999